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Exenatide-loaded inside-porous poly(lactic-co-glycolic acid) microspheres as a long-acting drug delivery system with improved release characteristics
The glucagon-like peptide-1 receptor agonist exenatide (EXT) is an effective treatment for type 2 diabetes. However, this peptide has a short biological half-life and the delayed release characteristic of current formulations limit its clinical application. Herein, we prepared EXT-loaded inside-poro...
Autores principales: | Zhai, Junqiu, Ou, Zhanlun, Zhong, Liuting, Wang, Yu-e, Cao, Li-Ping, Guan, Shixia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875555/ https://www.ncbi.nlm.nih.gov/pubmed/33241694 http://dx.doi.org/10.1080/10717544.2020.1850919 |
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