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Nitrous anhydrase activity of carbonic anhydrase II: cysteine is required for nitric oxide (NO) dependent phosphorylation of VASP in human platelets

The carbonic anhydrase (CA) family does not only catalyse the reversible hydration of CO(2) to bicarbonate, but it also possesses esterase and phosphatase activity. Recently, bovine CA II and human CA II have been reported to convert inorganic nitrite (O=N-O(−)) to nitric oxide (NO) and nitrous anhy...

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Detalles Bibliográficos
Autores principales: Tsikas, Dimitrios, Gambaryan, Stepan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875556/
https://www.ncbi.nlm.nih.gov/pubmed/33508993
http://dx.doi.org/10.1080/14756366.2021.1874946