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Behavioral role of PACAP signaling reflects its selective distribution in glutamatergic and GABAergic neuronal subpopulations

The neuropeptide PACAP, acting as a co-transmitter, increases neuronal excitability, which may enhance anxiety and arousal associated with threat conveyed by multiple sensory modalities. The distribution of neurons expressing PACAP and its receptor, PAC1, throughout the mouse nervous system was dete...

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Detalles Bibliográficos
Autores principales: Zhang, Limei, Hernandez, Vito S, Gerfen, Charles R, Jiang, Sunny Z, Zavala, Lilian, Barrio, Rafael A, Eiden, Lee E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875564/
https://www.ncbi.nlm.nih.gov/pubmed/33463524
http://dx.doi.org/10.7554/eLife.61718