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Structural insights and molecular dynamics into the inhibitory mechanism of a Kunitz-type trypsin inhibitor from Tamarindus indica L

Trypsin inhibitors from tamarind seed have been studied in vitro and in preclinical studies for the treatment of obesity, its complications and associated comorbidities. It is still necessary to fully understand the structure and behaviour of these molecules. We purifed this inhibitor, sequenced de...

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Detalles Bibliográficos
Autores principales: de Medeiros, Amanda Fernandes, de Souza, Beatriz Blenda Pinheiro, Coutinho, Lucas Pinheiro, Murad, Aline Melro, dos Santos, Paula Ivani Medeiros, Monteiro, Norberto de Kássio Vieira, dos Santos, Elizeu Antunes, Maciel, Bruna Leal Lima, de Araújo Morais, Ana Heloneida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875565/
https://www.ncbi.nlm.nih.gov/pubmed/33491503
http://dx.doi.org/10.1080/14756366.2021.1876686