Cargando…
Structural insights and molecular dynamics into the inhibitory mechanism of a Kunitz-type trypsin inhibitor from Tamarindus indica L
Trypsin inhibitors from tamarind seed have been studied in vitro and in preclinical studies for the treatment of obesity, its complications and associated comorbidities. It is still necessary to fully understand the structure and behaviour of these molecules. We purifed this inhibitor, sequenced de...
Autores principales: | de Medeiros, Amanda Fernandes, de Souza, Beatriz Blenda Pinheiro, Coutinho, Lucas Pinheiro, Murad, Aline Melro, dos Santos, Paula Ivani Medeiros, Monteiro, Norberto de Kássio Vieira, dos Santos, Elizeu Antunes, Maciel, Bruna Leal Lima, de Araújo Morais, Ana Heloneida |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875565/ https://www.ncbi.nlm.nih.gov/pubmed/33491503 http://dx.doi.org/10.1080/14756366.2021.1876686 |
Ejemplares similares
-
Biochemical characterisation of a Kunitz-type inhibitor from Tamarindus indica L. seeds and its efficacy in reducing plasma leptin in an experimental model of obesity
por: de Medeiros, Amanda Fernandes, et al.
Publicado: (2018) -
Trypsin inhibitor from tamarindus indica L. seeds reduces weight gain and food consumption and increases plasmatic cholecystokinin levels
por: do Nascimento Campos Ribeiro, Joycellane Alline, et al.
Publicado: (2015) -
An Insulin Receptor-Binding Multifunctional Protein from Tamarindus indica L. Presents a Hypoglycemic Effect in a Diet-Induced Type 2 Diabetes—Preclinical Study
por: Costa, Izael, et al.
Publicado: (2022) -
Tamarind (Tamarindus indica L.) Seed a Candidate Protein Source with Potential for Combating SARS-CoV-2 Infection in Obesity
por: Morais, Ana H. de A., et al.
Publicado: (2021) -
Tamarindus indica: Extent of explored potential
por: Bhadoriya, Santosh Singh, et al.
Publicado: (2011)