Hypoxic tumor-derived exosomal circular RNA SETDB1 promotes invasive growth and EMT via the miR-7/Sp1 axis in lung adenocarcinoma

Hypoxia is a common feature of solid tumors and has been associated with tumor aggressiveness and poor prognosis. Exosomes are involved in mediating cellular-environment interactions. Circular RNAs (circRNAs) are a class of non-coding RNA broadly found in cells and exosomes. However, the functions a...

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Detalles Bibliográficos
Autores principales: Xu, Li, Liao, Wei-Lin, Lu, Qi-Jue, Zhang, Peng, Zhu, Ji, Jiang, Ge-Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875767/
https://www.ncbi.nlm.nih.gov/pubmed/33614250
http://dx.doi.org/10.1016/j.omtn.2021.01.019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875767/
https://www.ncbi.nlm.nih.gov/pubmed/33614250
http://dx.doi.org/10.1016/j.omtn.2021.01.019

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