Cargando…

The HIF‐1α/p53/miRNA‐34a/Klotho axis in retinal pigment epithelial cells promotes subretinal fibrosis and exacerbates choroidal neovascularization

Wet age‐related macular degeneration (wAMD), characterized by choroidal neovascularization (CNV), is a leading cause of irreversible vision loss among elderly people in developed nations. Subretinal fibrosis, mediated by epithelial‐mesenchymal transition (EMT) of retinal pigment epithelium (RPE) cel...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xie, Laiqing, Wang, Ying, Li, Quan, Ji, Xiaoyan, Tu, Yuanyuan, Du, Shu, Lou, Hui, Zeng, Xinwei, Zhu, Linling, Zhang, Ji, Zhu, Manhui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875902/ https://www.ncbi.nlm.nih.gov/pubmed/33438362 http://dx.doi.org/10.1111/jcmm.16272

Ejemplares similares

Modulation of choroidal neovascularization by subretinal injection of retinal pigment epithelium and polystyrene microbeads
por: Schmack, Ingo, et al.
Publicado: (2009)

Brolucizumab for Choroidal Neovascular Membrane with Pigment Epithelial Tear and Subretinal Fluid
por: Bilgic, Alper, et al.
Publicado: (2021)

Spontaneous Resolution of Subretinal Hemorrhage Secondary to Choroidal Osteoma Unassociated with Choroidal Neovascularization
por: Koylu, Mehmet Talay, et al.
Publicado: (2014)

CSF1/CSF1R-mediated Crosstalk Between Choroidal Vascular Endothelial Cells and Macrophages Promotes Choroidal Neovascularization
por: Zhou, Yamei, et al.
Publicado: (2021)

Iatrogenic choroidal neovascularization associated with subretinal gene therapy surgery
por: Price, Kenneth W., et al.
Publicado: (2022)

Cabozantinib, a Multityrosine Kinase Inhibitor of MET and VEGF Receptors Which Suppresses Mouse Laser-Induced Choroidal Neovascularization
por: Zhang, Xiaoli, et al.
Publicado: (2020)

The COX-2-Selective Antagonist (NS-398) Inhibits Choroidal Neovascularization and Subretinal Fibrosis
por: Zhang, Ruoshuang, et al.
Publicado: (2016)

Treatment response to intravitreal bevacizumab in small pigmented choroidal lesions with subretinal fluid
por: Lee, Junwon, et al.
Publicado: (2019)

Lycopene inhibits endothelial‐to‐mesenchymal transition of choroidal vascular endothelial cells in laser‐induced mouse choroidal neovascularization
por: Li, Lele, et al.
Publicado: (2023)

A Novel Platelet-Activating Factor Receptor Antagonist Inhibits Choroidal Neovascularization and Subretinal Fibrosis
por: Zhang, Han, et al.
Publicado: (2013)

Reliability and reproducibility of a rodent model of choroidal neovascularization based on the subretinal injection of polyethylene glycol
por: Fernandez-Bueno, Ivan, et al.
Publicado: (2019)

Is subretinal surgery feasible for a non-responsive juxtafoveal type 2 choroidal neovascular membrane?
por: Quiroz-Mercado, Hugo, et al.
Publicado: (2019)

Blockade of Platelet-Derived Growth Factor Signaling Inhibits Choroidal Neovascularization and Subretinal Fibrosis in Mice
por: Liu, Ye, et al.
Publicado: (2020)

A Two-Stage Laser-Induced Mouse Model of Subretinal Fibrosis Secondary to Choroidal Neovascularization
por: Little, Karis, et al.
Publicado: (2020)

LncRNA MALAT1 knockdown inhibits the development of choroidal neovascularization
por: Zhang, Xiaoli, et al.
Publicado: (2023)

Correlation of In Vivo and In Vitro Methods in Measuring Choroidal Vascularization Volumes Using a Subretinal Injection Induced Choroidal Neovascularization Model
por: Nie, Chuang, et al.
Publicado: (2015)

Characteristics and response of subretinal hyperreflective material to anti-vascular endothelial growth factor in myopic choroidal neovascularization
por: Huang, Chien-Jung, et al.
Publicado: (2023)

Erythropoietin Signaling Increases Choroidal Macrophages and Cytokine Expression, and Exacerbates Choroidal Neovascularization
por: Bretz, Colin A., et al.
Publicado: (2018)

Multimodal imaging of laser-induced choroidal neovascularization in pigmented rabbits
por: Nguyen, Van Phuc, et al.
Publicado: (2023)

Targeting Hif1a rescues cone degeneration and prevents subretinal neovascularization in a model of chronic hypoxia
por: Barben, Maya, et al.
Publicado: (2018)

Subretinal Saline Protects the Neuroretina From Thermic Damage During Laser Induction of Experimental Choroidal Neovascularization in Pigs
por: Hansen, Silja, et al.
Publicado: (2021)

Time-Lag between Subretinal Fluid and Pigment Epithelial Detachment Reduction after Polypoidal Choroidal Vasculopathy Treatment
por: Chae, Ju Byung, et al.
Publicado: (2011)

Choroidal pericytes promote subretinal fibrosis after experimental photocoagulation
por: Luo, Xueting, et al.
Publicado: (2018)

Fruquintinib inhibits VEGF/VEGFR2 axis of choroidal endothelial cells and M1-type macrophages to protect against mouse laser-induced choroidal neovascularization
por: Liu, Xiaojuan, et al.
Publicado: (2020)

A Case of Choroidal Neovascularization Secondary to Unilateral Retinal Pigment Epithelium Dysgenesis
por: Shimoyama, Tsuyoshi, et al.
Publicado: (2014)

Choroidal Neovascularization Induced by Immunogenic Alteration of the Retinal Pigment Epithelium in Dengue Fever
por: Veloso, Carlos Eduardo, et al.
Publicado: (2015)

Pigment Epithelium-Derived Factor as a Possible Treatment Agent for Choroidal Neovascularization
por: Xi, Lei
Publicado: (2020)

A reproducible and quantifiable model of choroidal neovascularization induced by VEGF A(165) after subretinal adenoviral gene transfer in the rabbit
por: Julien, Sylvie, et al.
Publicado: (2008)

Characteristics and Associated Factors of Flat Irregular Pigment Epithelial Detachment With Choroidal Neovascularization in Chronic Central Serous Chorioretinopathy
por: Su, Yongyue, et al.
Publicado: (2021)

Spectral domain-optical coherence tomography retinal biomarkers in choroidal neovascularization of multifocal choroiditis, myopic choroidal neovascularization, and idiopathic choroidal neovascularization
por: Gao, Rui, et al.
Publicado: (2021)

Subretinal lipid exudation associated with untreated choroidal melanoma
por: Minija, C K, et al.
Publicado: (2011)

Klotho controls the brain–immune system interface in the choroid plexus
por: Zhu, Lei, et al.
Publicado: (2018)

Sema3f Protects Against Subretinal Neovascularization In Vivo
por: Sun, Ye, et al.
Publicado: (2017)

PKR promotes choroidal neovascularization via upregulating the PI3K/Akt signaling pathway in VEGF expression
por: Zhu, Manhui, et al.
Publicado: (2016)

Choroidal neovascularization associated with combined hamartoma of retina and retinal pigment epithelium: Multimodal imaging
por: Gupta, Rajan, et al.
Publicado: (2018)

Subretinal pigment epithelial infiltrates in primary vitreoretinal lymphoma
por: Vasconcelos-Santos, Daniel Vítor, et al.
Publicado: (2011)

Subretinal pigment epithelium cleft: A sign of caution
por: Babu, Naresh, et al.
Publicado: (2019)

Inflammatory Choroidal Neovascularization
por: Neri, Piergiorgi, et al.
Publicado: (2009)

Fluorescein angiography of subretinal neovascular membrane in parafoveal telangiectasia type II demonstrating retino-retinal, retino-subretinal anastomosis
por: Megur, Bharathi, et al.
Publicado: (2016)

Rapid displacement of subretinal hemorrhage from a choroidal neovascular membrane with intravitreal C3F8 gas and face-down positioning()
por: Adrean, Sean D., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_d9dtrng81podncema0c8snid3k