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Knockout of Akt1/2 suppresses the metastasis of human prostate cancer cells CWR22rv1 in vitro and in vivo

Although primary androgen deprivation therapy resulted in tumour regression, unfortunately, majority of prostate cancer progress to a lethal castration‐resistant prostate cancer, finally die to metastasis. The mutual feedback between AKT and AR pathways plays a vital role in the progression and meta...

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Detalles Bibliográficos
Autores principales: Su, Bing, Zhang, Lijuan, Zhuang, Wenfang, Zhang, Wei, Chen, Xiaofan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875906/
https://www.ncbi.nlm.nih.gov/pubmed/33377281
http://dx.doi.org/10.1111/jcmm.16246