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Regulation of lipid metabolism by the unfolded protein response
The endoplasmic reticulum (ER) is the site of protein folding and secretion, Ca(2+) storage and lipid synthesis in eukaryotic cells. Disruption to protein folding or Ca(2+) homeostasis in the ER leads to the accumulation of unfolded proteins, a condition known as ER stress. This leads to activation...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875919/ https://www.ncbi.nlm.nih.gov/pubmed/33398919 http://dx.doi.org/10.1111/jcmm.16255 |