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Regulation of lipid metabolism by the unfolded protein response

The endoplasmic reticulum (ER) is the site of protein folding and secretion, Ca(2+) storage and lipid synthesis in eukaryotic cells. Disruption to protein folding or Ca(2+) homeostasis in the ER leads to the accumulation of unfolded proteins, a condition known as ER stress. This leads to activation...

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Detalles Bibliográficos
Autores principales: Moncan, Matthieu, Mnich, Katarzyna, Blomme, Arnaud, Almanza, Aitor, Samali, Afshin, Gorman, Adrienne M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875919/
https://www.ncbi.nlm.nih.gov/pubmed/33398919
http://dx.doi.org/10.1111/jcmm.16255