Cargando…

Regulation of lipid metabolism by the unfolded protein response

The endoplasmic reticulum (ER) is the site of protein folding and secretion, Ca(2+) storage and lipid synthesis in eukaryotic cells. Disruption to protein folding or Ca(2+) homeostasis in the ER leads to the accumulation of unfolded proteins, a condition known as ER stress. This leads to activation...

Descripción completa

Detalles Bibliográficos
Autores principales:	Moncan, Matthieu, Mnich, Katarzyna, Blomme, Arnaud, Almanza, Aitor, Samali, Afshin, Gorman, Adrienne M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Reviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875919/ https://www.ncbi.nlm.nih.gov/pubmed/33398919 http://dx.doi.org/10.1111/jcmm.16255

Ejemplares similares

An Emerging Role for the Unfolded Protein Response in Pancreatic Cancer
por: Robinson, Claire M., et al.
Publicado: (2021)

The Unfolded Protein Response in Breast Cancer
por: McGrath, Eoghan P., et al.
Publicado: (2018)

Regulated IRE1α-dependent decay (RIDD)-mediated reprograming of lipid metabolism in cancer
por: Almanza, Aitor, et al.
Publicado: (2022)

Insights into the structure and function of the RNA ligase RtcB
por: Moncan, Matthieu, et al.
Publicado: (2023)

Unfolded proteins and endoplasmic reticulum stress in neurodegenerative disorders
por: Doyle, Karen M, et al.
Publicado: (2011)

Methods for Monitoring Endoplasmic Reticulum Stress and the Unfolded Protein Response
por: Samali, Afshin, et al.
Publicado: (2010)

Drugging the unfolded protein response in acute leukemias
por: Kharabi Masouleh, Behzad, et al.
Publicado: (2015)

Cellular Stress Responses: Cell Survival and Cell Death
por: Fulda, Simone, et al.
Publicado: (2010)

Heat shock preconditioning protects against ER stress-induced apoptosis through the regulation of the BH3-only protein BIM
por: Kennedy, Donna, et al.
Publicado: (2014)

miRNA signature of unfolded protein response in H9c2 rat cardiomyoblasts
por: Read, Danielle E, et al.
Publicado: (2014)

Endoplasmic Reticulum Stress-Regulated Chaperones as a Serum Biomarker Panel for Parkinson’s Disease
por: Mnich, Katarzyna, et al.
Publicado: (2022)

Lipid-dependent regulation of the unfolded protein response
por: Volmer, Romain, et al.
Publicado: (2015)

The stressosome, a caspase‐8‐activating signalling complex assembled in response to cell stress in an ATG5‐mediated manner
por: Mnich, Katarzyna, et al.
Publicado: (2021)

Autophagy, Apoptosis, the Unfolded Protein Response, and Lung Function in Idiopathic Pulmonary Fibrosis
por: Sharma, Pawan, et al.
Publicado: (2021)

PERK regulated miR-424(322)-503 cluster fine-tunes activation of IRE1 and ATF6 during Unfolded Protein Response
por: Gupta, Ananya, et al.
Publicado: (2015)

Simvastatin Induces Unfolded Protein Response and Enhances Temozolomide-Induced Cell Death in Glioblastoma Cells
por: Dastghaib, Sanaz, et al.
Publicado: (2020)

Downregulation of miR-17-92 Cluster by PERK Fine-Tunes Unfolded Protein Response Mediated Apoptosis
por: Read, Danielle E., et al.
Publicado: (2021)

New insights into IRE1α activation and function in anti-tumor immunity
por: Logue, Susan E., et al.
Publicado: (2022)

Unfolded Protein Responses With or Without Unfolded Proteins?
por: Snapp, Erik L.
Publicado: (2012)

Inhibition of IRE1 RNase activity modulates the tumor cell secretome and enhances response to chemotherapy
por: Logue, Susan E., et al.
Publicado: (2018)

The unfolded protein response modulators GSK2606414 and KIRA6 are potent KIT inhibitors
por: Mahameed, Mohamed, et al.
Publicado: (2019)

Regulation of the unfolded protein response by microRNAs
por: Bartoszewska, Sylwia, et al.
Publicado: (2013)

Regulation of the Homeostatic Unfolded Protein Response in Diabetic Nephropathy
por: Wang, Hongjie, et al.
Publicado: (2022)

Regulation of hedgehog Ligand Expression by the N-End Rule Ubiquitin-Protein Ligase Hyperplastic Discs and the Drosophila GSK3β Homologue, Shaggy
por: Moncrieff, Sophie, et al.
Publicado: (2015)

The unfolded protein response signaling and retinal Müller cell metabolism
por: Kelly, Kristen, et al.
Publicado: (2018)

Unfolding the Unfolded Protein Response: Unique Insights into Brain Ischemia
por: Sanderson, Thomas H., et al.
Publicado: (2015)

Melanoma and the Unfolded Protein Response
por: Sykes, Erin K., et al.
Publicado: (2016)

Herpesviruses and the Unfolded Protein Response
por: Johnston, Benjamin P., et al.
Publicado: (2019)

The Unfolded Protein Response: An Overview
por: Read, Adam, et al.
Publicado: (2021)

Cell Stress and Cell Death
por: Samali, Afshin, et al.
Publicado: (2010)

Merits and pitfalls of conventional and covalent docking in identifying new hydroxyl aryl aldehyde like compounds as human IRE1 inhibitors
por: Carlesso, Antonio, et al.
Publicado: (2019)

Binding Analysis of the Inositol-Requiring Enzyme 1 Kinase Domain
por: Carlesso, Antonio, et al.
Publicado: (2018)

Effect of Kinase Inhibiting RNase Attenuator (KIRA) Compounds on the Formation of Face-to-Face Dimers of Inositol-Requiring Enzyme 1: Insights from Computational Modeling
por: Carlesso, Antonio, et al.
Publicado: (2019)

Molecular modeling provides a structural basis for PERK inhibitor selectivity towards RIPK1
por: Chintha, Chetan, et al.
Publicado: (2020)

Regulation of basal cellular physiology by the homeostatic unfolded protein response
por: Rutkowski, D. Thomas, et al.
Publicado: (2010)

The mitochondrial unfolded protein response and mitohormesis: a perspective on metabolic diseases
por: Yi, Hyon-Seung, et al.
Publicado: (2018)

Unfolded Protein Response and Cancer
por: Wu, Lihua, et al.
Publicado: (2014)

Membrane biogenesis and the unfolded protein response
por: Ron, David, et al.
Publicado: (2004)

Putting the brakes on the unfolded protein response
por: Sicheri, Frank, et al.
Publicado: (2011)

The unfolded protein response in hereditary haemochromatosis
por: De Almeida, SF, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_n021d2bhqsbtuhkit6c6c8gmoe