Protein arginine methyltransferase 5 (PRMT5) activates WNT/β‐catenin signalling in breast cancer cells via epigenetic silencing of DKK1 and DKK3

Protein arginine methyltransferase 5 (PRMT5) activity is dysregulated in many aggressive cancers and its enhanced levels are associated with increased tumour growth and survival. However, the role of PRMT5 in breast cancer remains underexplored. In this study, we show that PRMT5 is overexpressed in...

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Detalles Bibliográficos
Autores principales: Shailesh, Harshita, Siveen, Kodappully S., Sif, Saïd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875925/
https://www.ncbi.nlm.nih.gov/pubmed/33462997
http://dx.doi.org/10.1111/jcmm.16260

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875925/
https://www.ncbi.nlm.nih.gov/pubmed/33462997
http://dx.doi.org/10.1111/jcmm.16260

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