The tyrosine kinase v‐Src modifies cytotoxicities of anticancer drugs targeting cell division

v‐Src oncogene causes cell transformation through its strong tyrosine kinase activity. We have revealed that v‐Src‐mediated cell transformation occurs at a low frequency and it is attributed to mitotic abnormalities‐mediated chromosome instability. v‐Src directly phosphorylates Tyr‐15 of cyclin‐depe...

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Detalles Bibliográficos
Autores principales: Yuki, Ryuzaburo, Hagino, Mari, Ueno, Sachi, Kuga, Takahisa, Saito, Youhei, Fukumoto, Yasunori, Yamaguchi, Noritaka, Yamaguchi, Naoto, Nakayama, Yuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875926/
https://www.ncbi.nlm.nih.gov/pubmed/33465289
http://dx.doi.org/10.1111/jcmm.16270

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875926/
https://www.ncbi.nlm.nih.gov/pubmed/33465289
http://dx.doi.org/10.1111/jcmm.16270

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