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Rea regulates microglial polarization and attenuates neuronal apoptosis via inhibition of the NF‐κB and MAPK signalings for spinal cord injury repair

Inflammation and neuronal apoptosis aggravate the secondary damage after spinal cord injury (SCI). Rehmannioside A (Rea) is a bioactive herbal extract isolated from Rehmanniae radix with low toxicity and neuroprotection effects. Rea treatment inhibited the release of pro‐inflammatory mediators from...

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Detalles Bibliográficos
Autores principales: Xiao, Shining, Wang, Chenggui, Yang, Quanming, Xu, Haibin, Lu, Jinwei, Xu, Kan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875927/
https://www.ncbi.nlm.nih.gov/pubmed/33369103
http://dx.doi.org/10.1111/jcmm.16220