Xanthatin synergizes with cisplatin to suppress homologous recombination through JAK2/STAT4/BARD1 axis in human NSCLC cells

Xanthatin (Xa) is a bicyclic sesquiterpene lactone identified from the plant Xanthium L. with impressive antitumor activity, but the role of Xa in non‐small cell lung cancer (NSCLC) is not known. Here we found that Xa inhibits proliferation, migration, invasion and induces apoptosis in NSCLC cells....

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Detalles Bibliográficos
Autores principales: Zhang, Jian, Yang, Sheng, Guan, Hongmei, Zhou, Jueyu, Gao, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875932/
https://www.ncbi.nlm.nih.gov/pubmed/33439503
http://dx.doi.org/10.1111/jcmm.16271

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875932/
https://www.ncbi.nlm.nih.gov/pubmed/33439503
http://dx.doi.org/10.1111/jcmm.16271

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