Eliciting the silent lucensomycin biosynthetic pathway in Streptomyces cyanogenus S136 via manipulation of the global regulatory gene adpA

Actinobacteria are among the most prolific sources of medically and agriculturally important compounds, derived from their biosynthetic gene clusters (BGCs) for specialized (secondary) pathways of metabolism. Genomics witnesses that the majority of actinobacterial BGCs are silent, most likely due to...

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Detalles Bibliográficos
Autores principales: Yushchuk, Oleksandr, Ostash, Iryna, Mösker, Eva, Vlasiuk, Iryna, Deneka, Maksym, Rückert, Christian, Busche, Tobias, Fedorenko, Victor, Kalinowski, Jörn, Süssmuth, Roderich D., Ostash, Bohdan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875965/
https://www.ncbi.nlm.nih.gov/pubmed/33568768
http://dx.doi.org/10.1038/s41598-021-82934-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875965/
https://www.ncbi.nlm.nih.gov/pubmed/33568768
http://dx.doi.org/10.1038/s41598-021-82934-6

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