Cavin1 intrinsically disordered domains are essential for fuzzy electrostatic interactions and caveola formation

Caveolae are spherically shaped nanodomains of the plasma membrane, generated by cooperative assembly of caveolin and cavin proteins. Cavins are cytosolic peripheral membrane proteins with negatively charged intrinsically disordered regions that flank positively charged α-helical regions. Here, we s...

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Detalles Bibliográficos
Autores principales: Tillu, Vikas A., Rae, James, Gao, Ya, Ariotti, Nicholas, Floetenmeyer, Matthias, Kovtun, Oleksiy, McMahon, Kerrie-Ann, Chaudhary, Natasha, Parton, Robert G., Collins, Brett M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875971/
https://www.ncbi.nlm.nih.gov/pubmed/33568658
http://dx.doi.org/10.1038/s41467-021-21035-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875971/
https://www.ncbi.nlm.nih.gov/pubmed/33568658
http://dx.doi.org/10.1038/s41467-021-21035-4

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