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Integrative analysis identifies bHLH transcription factors as contributors to Parkinson’s disease risk mechanisms

Genome-wide association studies (GWAS) have identified multiple genetic risk signals for Parkinson’s disease (PD), however translation into underlying biological mechanisms remains scarce. Genomic functional annotations of neurons provide new resources that may be integrated into analyses of GWAS fi...

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Detalles Bibliográficos
Autores principales: Berge-Seidl, Victoria, Pihlstrøm, Lasse, Toft, Mathias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875985/
https://www.ncbi.nlm.nih.gov/pubmed/33568722
http://dx.doi.org/10.1038/s41598-021-83087-2