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A novel canine reference genome resolves genomic architecture and uncovers transcript complexity

We present GSD_1.0, a high-quality domestic dog reference genome with chromosome length scaffolds and contiguity increased 55-fold over CanFam3.1. Annotation with generated and existing long and short read RNA-seq, miRNA-seq and ATAC-seq, revealed that 32.1% of lifted over CanFam3.1 gaps harboured p...

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Detalles Bibliográficos
Autores principales: Wang, Chao, Wallerman, Ola, Arendt, Maja-Louise, Sundström, Elisabeth, Karlsson, Åsa, Nordin, Jessika, Mäkeläinen, Suvi, Pielberg, Gerli Rosengren, Hanson, Jeanette, Ohlsson, Åsa, Saellström, Sara, Rönnberg, Henrik, Ljungvall, Ingrid, Häggström, Jens, Bergström, Tomas F., Hedhammar, Åke, Meadows, Jennifer R. S., Lindblad-Toh, Kerstin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875987/
https://www.ncbi.nlm.nih.gov/pubmed/33568770
http://dx.doi.org/10.1038/s42003-021-01698-x