Functionally selective activation of the dopamine receptor D(2) is mirrored by the protein expression profiles

The development of functionally selective or biased ligands is a promising approach towards drugs with less side effects. Biased ligands for G protein-coupled receptors can selectively induce G protein activation or β-arrestin recruitment. The consequences of this selective action on cellular functi...

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Detalles Bibliográficos
Autores principales: Wenk, Deborah, Ignatchenko, Vladimir, Macklin, Andrew, Hübner, Harald, Gmeiner, Peter, Weikert, Dorothée, Pischetsrieder, Monika, Kislinger, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875989/
https://www.ncbi.nlm.nih.gov/pubmed/33568753
http://dx.doi.org/10.1038/s41598-021-83038-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7875989/
https://www.ncbi.nlm.nih.gov/pubmed/33568753
http://dx.doi.org/10.1038/s41598-021-83038-x

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