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Global mapping of protein–metabolite interactions in Saccharomyces cerevisiae reveals that Ser-Leu dipeptide regulates phosphoglycerate kinase activity

Protein–metabolite interactions are of crucial importance for all cellular processes but remain understudied. Here, we applied a biochemical approach named PROMIS, to address the complexity of the protein–small molecule interactome in the model yeast Saccharomyces cerevisiae. By doing so, we provide...

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Detalles Bibliográficos
Autores principales: Luzarowski, Marcin, Vicente, Rubén, Kiselev, Andrei, Wagner, Mateusz, Schlossarek, Dennis, Erban, Alexander, de Souza, Leonardo Perez, Childs, Dorothee, Wojciechowska, Izabela, Luzarowska, Urszula, Górka, Michał, Sokołowska, Ewelina M., Kosmacz, Monika, Moreno, Juan C., Brzezińska, Aleksandra, Vegesna, Bhavana, Kopka, Joachim, Fernie, Alisdair R., Willmitzer, Lothar, Ewald, Jennifer C., Skirycz, Aleksandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876005/
https://www.ncbi.nlm.nih.gov/pubmed/33568709
http://dx.doi.org/10.1038/s42003-021-01684-3