BCAT1 decreases the sensitivity of cancer cells to cisplatin by regulating mTOR-mediated autophagy via branched-chain amino acid metabolism

Cisplatin is one of the most effective chemotherapy drugs and is widely used in the treatment of cancer, including hepatocellular carcinoma (HCC) and cervical cancer, but its therapeutic benefit is limited by the development of resistance. Our previous studies demonstrated that BCAT1 promoted cell p...

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Detalles Bibliográficos
Autores principales: Luo, Lifang, Sun, Wenjing, Zhu, Weijian, Li, Shuhan, Zhang, Wenqi, Xu, Xiaohui, Fang, Daoquan, Grahn, Tan Hooi Min, Jiang, Lei, Zheng, Yihu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876012/
https://www.ncbi.nlm.nih.gov/pubmed/33568627
http://dx.doi.org/10.1038/s41419-021-03456-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876012/
https://www.ncbi.nlm.nih.gov/pubmed/33568627
http://dx.doi.org/10.1038/s41419-021-03456-7

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