Anti-inflammatory dopamine- and serotonin-based endocannabinoid epoxides reciprocally regulate cannabinoid receptors and the TRPV1 channel

The endocannabinoid system is a promising target to mitigate pain as the endocannabinoids are endogenous ligands of the pain-mediating receptors—cannabinoid receptors 1 and 2 (CB1 and CB2) and TRPV1. Herein, we report on a class of lipids formed by the epoxidation of N-arachidonoyl-dopamine (NADA) a...

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Detalles Bibliográficos
Autores principales: Arnold, William R., Carnevale, Lauren N., Xie, Zili, Baylon, Javier L., Tajkhorshid, Emad, Hu, Hongzhen, Das, Aditi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876028/
https://www.ncbi.nlm.nih.gov/pubmed/33568652
http://dx.doi.org/10.1038/s41467-021-20946-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876028/
https://www.ncbi.nlm.nih.gov/pubmed/33568652
http://dx.doi.org/10.1038/s41467-021-20946-6

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