Cargando…

Anti-inflammatory dopamine- and serotonin-based endocannabinoid epoxides reciprocally regulate cannabinoid receptors and the TRPV1 channel

The endocannabinoid system is a promising target to mitigate pain as the endocannabinoids are endogenous ligands of the pain-mediating receptors—cannabinoid receptors 1 and 2 (CB1 and CB2) and TRPV1. Herein, we report on a class of lipids formed by the epoxidation of N-arachidonoyl-dopamine (NADA) a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Arnold, William R., Carnevale, Lauren N., Xie, Zili, Baylon, Javier L., Tajkhorshid, Emad, Hu, Hongzhen, Das, Aditi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876028/ https://www.ncbi.nlm.nih.gov/pubmed/33568652 http://dx.doi.org/10.1038/s41467-021-20946-6

Ejemplares similares

Cannabinoids, Endocannabinoids and Sleep
por: Kesner, Andrew J., et al.
Publicado: (2020)

The Endocannabinoid System, Cannabinoids, and Pain
por: Fine, Perry G., et al.
Publicado: (2013)

Endocannabinoid activation of the TRPV1 ion channel is distinct from activation by capsaicin
por: Li, Yanxin, et al.
Publicado: (2021)

Impact of Cannabis, Cannabinoids, and Endocannabinoids in the Lungs
por: Turcotte, Caroline, et al.
Publicado: (2016)

Molecular Advances on Cannabinoid and Endocannabinoid Research
por: Meccariello, Rosaria
Publicado: (2023)

Terpenoids Commonly Found in Cannabis sativa Do Not Modulate the Actions of Phytocannabinoids or Endocannabinoids on TRPA1 and TRPV1 Channels
por: Heblinski, Marika, et al.
Publicado: (2020)

Diverse TRPV1 responses to cannabinoids
por: Starkus, J., et al.
Publicado: (2019)

The Interplay between the Endocannabinoid System, Epilepsy and Cannabinoids
por: Kwan Cheung, Keith A., et al.
Publicado: (2019)

13. ENDOCANNABINOID MODULATION OF DOPAMINE NEUROTRANSMISSION
por: Bloomfield, Michael
Publicado: (2018)

Role of cannabinoids and the endocannabinoid system in modulation of diabetic cardiomyopathy
por: El-Azab, Mona F, et al.
Publicado: (2022)

Structures and membrane interactions of native serotonin transporter in complexes with psychostimulants
por: Yang, Dongxue, et al.
Publicado: (2023)

The endocannabinoid systemʼs involvement in motor development relies on cannabinoid receptors, TRP channels, and Sonic Hedgehog signaling
por: Khara, Lakhan S., et al.
Publicado: (2023)

Gating of human TRPV3 in a lipid bilayer
por: Deng, Zengqin, et al.
Publicado: (2020)

TRPV1 and Endocannabinoids: Emerging Molecular Signals that Modulate Mammalian Vision
por: Ryskamp, Daniel A., et al.
Publicado: (2014)

Involvement of TRPV4 in serotonin-evoked scratching
por: Akiyama, Tasuku, et al.
Publicado: (2016)

Cannabinoids and Endocannabinoid System Changes in Intestinal Inflammation and Colorectal Cancer
por: Cherkasova, Viktoriia, et al.
Publicado: (2021)

Tribute to Professor Raphael Mechoulam, The Founder of Cannabinoid and Endocannabinoid Research
por: Maccarrone, Mauro
Publicado: (2022)

Endocannabinoid System and Exogenous Cannabinoids in Depression and Anxiety: A Review
por: Hasbi, Ahmed, et al.
Publicado: (2023)

Endocannabinoid–Dopamine Interactions in Striatal Synaptic Plasticity
por: Mathur, Brian N., et al.
Publicado: (2012)

13.1 ENDOCANNABINOID MODULATION OF DOPAMINE NEUROTRANSMISSION
por: Moreira, Fabricio
Publicado: (2018)

Endocannabinoids and Dopamine Balance Basal Ganglia Output
por: Gorodetski, Lilach, et al.
Publicado: (2021)

Maternal high-fat diet decreases milk endocannabinoids with sex-specific changes in the cannabinoid and dopamine signaling and food preference in rat offspring
por: Dias-Rocha, Camilla P., et al.
Publicado: (2023)

Importance of Non-Selective Cation Channel TRPV4 Interaction with Cytoskeleton and Their Reciprocal Regulations in Cultured Cells
por: Goswami, Chandan, et al.
Publicado: (2010)

Reciprocal regulation among TRPV1 channels and phosphoinositide 3-kinase in response to nerve growth factor
por: Stratiievska, Anastasiia, et al.
Publicado: (2018)

Characterizing the Membrane-Bound State of Cytochrome P450 3A4: Structure, Depth of Insertion, and Orientation
por: Baylon, Javier L., et al.
Publicado: (2013)

A molecular determinant of phosphoinositide affinity in mammalian TRPV channels
por: Velisetty, Phanindra, et al.
Publicado: (2016)

Effects of MDMA on Extracellular Dopamine and Serotonin Levels in Mice Lacking Dopamine and/or Serotonin Transporters
por: Hagino, Y, et al.
Publicado: (2011)

An unexpected role for TRPV4 in serotonin-mediated itch
por: Snyder, Lindsey M., et al.
Publicado: (2016)

Role of Endocannabinoids and Cannabinoid-1 Receptors in Cerebrocortical Blood Flow Regulation
por: Iring, András, et al.
Publicado: (2013)

Cannabinoid Receptors and the Endocannabinoid System: Signaling and Function in the Central Nervous System
por: Zou, Shenglong, et al.
Publicado: (2018)

Cannabis, Cannabinoids, and the Endocannabinoid System—Is there Therapeutic Potential for Inflammatory Bowel Disease?
por: Ambrose, Tim, et al.
Publicado: (2019)

Cannabinoids and the endocannabinoid system in reward processing and addiction: from mechanisms to interventions 
por: Spanagel, Rainer
Publicado: (2020)

New Insights in the Involvement of the Endocannabinoid System and Natural Cannabinoids in Nicotine Dependence
por: Saravia, Rocio, et al.
Publicado: (2021)

Role of integrating cannabinoids and the endocannabinoid system in neonatal hypoxic-ischaemic encephalopathy
por: Xiao, Jie, et al.
Publicado: (2023)

Expression of the endocannabinoid system and response to cannabinoid components by the human fetal testis
por: Dochez-Arnault, J., et al.
Publicado: (2023)

To Act or Not to Act: Endocannabinoid/Dopamine Interactions in Decision-Making
por: Hernandez, Giovanni, et al.
Publicado: (2015)

TRP Channels as Drug Targets to Relieve Itch
por: Xie, Zili, et al.
Publicado: (2018)

Turning Over a New Leaf: Cannabinoid and Endocannabinoid Modulation of Immune Function
por: Cabral, Guy A., et al.
Publicado: (2015)

Polarized cellular patterns of endocannabinoid production and detection shape cannabinoid signaling in neurons
por: Ladarre, Delphine, et al.
Publicado: (2015)

Cannabinoids and endocannabinoids as therapeutics for nervous system disorders: preclinical models and clinical studies
por: Duncan, R. Scott, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_fuuegkv9bvotv7src9r8p34456