Nascent RNA sequencing identifies a widespread sigma70-dependent pausing regulated by Gre factors in bacteria

Promoter-proximal pausing regulates eukaryotic gene expression and serves as checkpoints to assemble elongation/splicing machinery. Little is known how broadly this type of pausing regulates transcription in bacteria. We apply nascent elongating transcript sequencing combined with RNase I footprinti...

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Detalles Bibliográficos
Autores principales: Sun, Zhe, Yakhnin, Alexander V., FitzGerald, Peter C., Mclntosh, Carl E., Kashlev, Mikhail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876045/
https://www.ncbi.nlm.nih.gov/pubmed/33568644
http://dx.doi.org/10.1038/s41467-021-21150-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876045/
https://www.ncbi.nlm.nih.gov/pubmed/33568644
http://dx.doi.org/10.1038/s41467-021-21150-2

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