CYK4 relaxes the bias in the off-axis motion by MKLP1 kinesin-6

Centralspindlin, a complex of the MKLP1 kinesin-6 and CYK4 GAP subunits, plays key roles in metazoan cytokinesis. CYK4-binding to the long neck region of MKLP1 restricts the configuration of the two MKLP1 motor domains in the centralspindlin. However, it is unclear how the CYK4-binding modulates the...

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Detalles Bibliográficos
Autores principales: Maruyama, Yohei, Sugawa, Mitsuhiro, Yamaguchi, Shin, Davies, Tim, Osaki, Toshihisa, Kobayashi, Takuya, Yamagishi, Masahiko, Takeuchi, Shoji, Mishima, Masanori, Yajima, Junichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876049/
https://www.ncbi.nlm.nih.gov/pubmed/33568771
http://dx.doi.org/10.1038/s42003-021-01704-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876049/
https://www.ncbi.nlm.nih.gov/pubmed/33568771
http://dx.doi.org/10.1038/s42003-021-01704-2

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