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Supraphysiological Levels of IL-2 in Jak3-Deficient Mice Promote Strong Proliferative Responses of Adoptively Transferred Naive CD8(+) T Cells
The antigen-independent, strong proliferative responses of naive CD8(+) T cells have been well demonstrated in a particular strain of mice lacking IL-2 receptors. This type of proliferation is mainly driven by common gamma-chain (γ(c)) cytokines, such as IL-2, IL-7, and IL-15, present at abnormally...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876067/ https://www.ncbi.nlm.nih.gov/pubmed/33584707 http://dx.doi.org/10.3389/fimmu.2020.616898 |