PF-429242, a Subtilisin Inhibitor, Is Effective in vitro Against Leishmania infantum

PF-429242 is an inhibitor of subtilisin, an important protease found in Leishmania. However, studies regarding the effect of PF-429242 on Leishmania are scarce. In this work we evaluated the antileishmanial effect of PF-429242 against Leishmania infantum and the mechanism involved in the death of th...

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Detalles Bibliográficos
Autores principales: Machado, Patrícia de Almeida, Gomes, Pollyanna Stephanie, Midlej, Victor, Coimbra, Elaine Soares, de Matos Guedes, Herbert Leonel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876069/
https://www.ncbi.nlm.nih.gov/pubmed/33584607
http://dx.doi.org/10.3389/fmicb.2021.583834

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876069/
https://www.ncbi.nlm.nih.gov/pubmed/33584607
http://dx.doi.org/10.3389/fmicb.2021.583834

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