A Novel Branched DNA-Based Flowcytometric Method for Single-Cell Characterization of Gene Therapy Products and Expression of Therapeutic Genes

Many preclinical and clinical studies of hematopoietic stem cell-based gene therapy (GT) are based on the use of lentiviruses as the vector of choice. Assessment of the vector titer and transduction efficiency of the cell product is critical for these studies. Efficacy and safety of the modified cel...

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Detalles Bibliográficos
Autores principales: Garcia-Perez, Laura, van Eggermond, Marja C.J.A., Maietta, Elisa, van der Hoorn, Marie-Louise P., Pike-Overzet, Karin, Staal, Frank J. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876092/
https://www.ncbi.nlm.nih.gov/pubmed/33584681
http://dx.doi.org/10.3389/fimmu.2020.607991

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876092/
https://www.ncbi.nlm.nih.gov/pubmed/33584681
http://dx.doi.org/10.3389/fimmu.2020.607991

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