Brain-derived neurotrophic factor in cerebrospinal fluid and plasma is not a biomarker for Huntington’s disease

Brain-derived neurotrophic factor (BDNF) is implicated in the survival of striatal neurons. BDNF function is reduced in Huntington’s disease (HD), possibly because mutant huntingtin impairs its cortico-striatal transport, contributing to striatal neurodegeneration. The BDNF trophic pathway is a ther...

Descripción completa

Detalles Bibliográficos
Autores principales: Ou, Zhen-Yi Andy, Byrne, Lauren M., Rodrigues, Filipe B., Tortelli, Rosanna, Johnson, Eileanoir B., Foiani, Martha S., Arridge, Marzena, De Vita, Enrico, Scahill, Rachael I., Heslegrave, Amanda, Zetterberg, Henrik, Wild, Edward J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876124/
https://www.ncbi.nlm.nih.gov/pubmed/33568689
http://dx.doi.org/10.1038/s41598-021-83000-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876124/
https://www.ncbi.nlm.nih.gov/pubmed/33568689
http://dx.doi.org/10.1038/s41598-021-83000-x

Ejemplares similares