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TRPV1 feed-forward sensitisation depends on COX2 upregulation in primary sensory neurons

Increased activity and excitability (sensitisation) of a series of molecules including the transient receptor potential ion channel, vanilloid subfamily, member 1 (TRPV1) in pain-sensing (nociceptive) primary sensory neurons are pivotal for developing pathological pain experiences in tissue injuries...

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Detalles Bibliográficos
Autores principales: Li, Tianci, Wang, Gaoge, Hui, Vivian Chin Chin, Saad, Daniel, de Sousa Valente, Joao, La Montanara, Paolo, Nagy, Istvan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876133/
https://www.ncbi.nlm.nih.gov/pubmed/33568699
http://dx.doi.org/10.1038/s41598-021-82829-6