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TRPV1 feed-forward sensitisation depends on COX2 upregulation in primary sensory neurons
Increased activity and excitability (sensitisation) of a series of molecules including the transient receptor potential ion channel, vanilloid subfamily, member 1 (TRPV1) in pain-sensing (nociceptive) primary sensory neurons are pivotal for developing pathological pain experiences in tissue injuries...
Autores principales: | Li, Tianci, Wang, Gaoge, Hui, Vivian Chin Chin, Saad, Daniel, de Sousa Valente, Joao, La Montanara, Paolo, Nagy, Istvan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876133/ https://www.ncbi.nlm.nih.gov/pubmed/33568699 http://dx.doi.org/10.1038/s41598-021-82829-6 |
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