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Plasma cells are enriched in localized prostate cancer in Black men and are associated with improved outcomes

Black men die more often of prostate cancer yet, interestingly, may derive greater survival benefits from immune-based treatment with sipuleucel-T. Since no signatures of immune-responsiveness exist for prostate cancer, we explored race-based immune-profiles to identify vulnerabilities. Here we show...

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Detalles Bibliográficos
Autores principales: Weiner, Adam B., Vidotto, Thiago, Liu, Yang, Mendes, Adrianna A., Salles, Daniela C., Faisal, Farzana A., Murali, Sanjana, McFarlane, Matthew, Imada, Eddie L., Zhao, Xin, Li, Ziwen, Davicioni, Elai, Marchionni, Luigi, Chinnaiyan, Arul M., Freedland, Stephen J., Spratt, Daniel E., Wu, Jennifer D., Lotan, Tamara L., Schaeffer, Edward M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876147/
https://www.ncbi.nlm.nih.gov/pubmed/33568675
http://dx.doi.org/10.1038/s41467-021-21245-w