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Mechanisms Governing Immunotherapy Resistance in Pancreatic Ductal Adenocarcinoma
Pancreatic ductal adenocarcinoma (PDA) is a lethal malignancy with an overall 5-year survival rate of 10%. Disease lethality is due to late diagnosis, early metastasis and resistance to therapy, including immunotherapy. PDA creates a robust fibroinflammatory tumor microenvironment that contributes t...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876239/ https://www.ncbi.nlm.nih.gov/pubmed/33584701 http://dx.doi.org/10.3389/fimmu.2020.613815 |