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Induced Expression of kir6.2 in A1 Astrocytes Propagates Inflammatory Neurodegeneration via Drp1-dependent Mitochondrial Fission

Glia-mediated inflammatory processes are crucial in the pathogenesis of Parkinson’s disease (PD). As the most abundant cells of the brain and active participants in neuroinflammatory responses, astrocytes largely propagate inflammatory signals and amplify neuronal loss. Hence, intensive control of a...

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Detalles Bibliográficos
Autores principales: Song, Nanshan, Zhu, Hong, Xu, Rong, Liu, Jiaqi, Fang, Yinquan, Zhang, Jing, Ding, Jianhua, Hu, Gang, Lu, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876245/
https://www.ncbi.nlm.nih.gov/pubmed/33584303
http://dx.doi.org/10.3389/fphar.2020.618992