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Is Senescence-Associated β-Galactosidase a Reliable in vivo Marker of Cellular Senescence During Embryonic Development?

During vertebrate embryonic development, cellular senescence occurs at multiple locations. To date, it has been accepted that when there has been induction of senescence in an embryonic tissue, β-galactosidase activity is detectable at a pH as high as 6.0, and this has been extensively used as a mar...

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Detalles Bibliográficos
Autores principales: de Mera-Rodríguez, José Antonio, Álvarez-Hernán, Guadalupe, Gañán, Yolanda, Martín-Partido, Gervasio, Rodríguez-León, Joaquín, Francisco-Morcillo, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876289/
https://www.ncbi.nlm.nih.gov/pubmed/33585480
http://dx.doi.org/10.3389/fcell.2021.623175