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Reduced CD5 on CD8(+) T Cells in Tumors but Not Lymphoid Organs Is Associated With Increased Activation and Effector Function
CD5, a member of the scavenger receptor cysteine-rich superfamily, is a marker for T cells and a subset of B cells (B1a). CD5 associates with T-cell and B-cell receptors and increased CD5 is an indication of B cell activation. In tumor-infiltrating lymphocytes (TILs) isolated from lung cancer patien...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876331/ https://www.ncbi.nlm.nih.gov/pubmed/33584650 http://dx.doi.org/10.3389/fimmu.2020.584937 |