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Reduced CD5 on CD8(+) T Cells in Tumors but Not Lymphoid Organs Is Associated With Increased Activation and Effector Function

CD5, a member of the scavenger receptor cysteine-rich superfamily, is a marker for T cells and a subset of B cells (B1a). CD5 associates with T-cell and B-cell receptors and increased CD5 is an indication of B cell activation. In tumor-infiltrating lymphocytes (TILs) isolated from lung cancer patien...

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Detalles Bibliográficos
Autores principales:	Alotaibi, Faizah, Vincent, Mark, Min, Wei-Ping, Koropatnick, James
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876331/ https://www.ncbi.nlm.nih.gov/pubmed/33584650 http://dx.doi.org/10.3389/fimmu.2020.584937

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