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The CRISPR-Cas Mechanism for Adaptive Immunity and Alternate Bacterial Functions Fuels Diverse Biotechnologies

Bacterial and archaeal CRISPR-Cas systems offer adaptive immune protection against foreign mobile genetic elements (MGEs). This function is regulated by sequence specific binding of CRISPR RNA (crRNA) to target DNA/RNA, with an additional requirement of a flanking DNA motif called the protospacer ad...

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Detalles Bibliográficos
Autores principales: Newsom, Sydney, Parameshwaran, Hari Priya, Martin, Lindsie, Rajan, Rakhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876343/
https://www.ncbi.nlm.nih.gov/pubmed/33585286
http://dx.doi.org/10.3389/fcimb.2020.619763