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MiR-146a-5p Mimic Inhibits NLRP3 Inflammasome Downstream Inflammatory Factors and CLIC4 in Neonatal Necrotizing Enterocolitis

Objective: Necrotizing enterocolitis (NEC) is a gastrointestinal emergency with a severe inflammation storm, intestinal necrosis, and perforation. MicroRNA-146a-5p (miR-146a-5p) has been reported to be a valuable anti-inflammatory factor in various intestinal inflammatory disorders. However, the rol...

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Detalles Bibliográficos
Autores principales: Chen, Jianglong, Chen, Tong, Zhou, Jin, Zhao, Xiuhao, Sheng, Qingfeng, Lv, Zhibao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876392/
https://www.ncbi.nlm.nih.gov/pubmed/33585442
http://dx.doi.org/10.3389/fcell.2020.594143