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Changes in the Immune Phenotype and Gene Expression Profile Driven by a Novel Tuberculosis Nanovaccine: Short and Long-Term Post-immunization

Deciphering protection mechanisms against Mycobacterium tuberculosis (Mtb) remains a critical challenge for the development of new vaccines and therapies. We analyze the phenotypic and transcriptomic profile in lung of a novel tuberculosis (TB) nanoparticle-based boosting mucosal vaccine Nano-FP1, w...

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Detalles Bibliográficos
Autores principales: Martínez-Pérez, Amparo, Igea, Ana, Estévez, Olivia, Ferreira, Catarina M., Torrado, Egídio, Castro, António Gil, Fernández, Carmen, Spetz, Anna-Lena, Adam, Lucille, López González, Moisés, Singh, Mahavir, Reljic, Rajko, González-Fernández, África
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876410/
https://www.ncbi.nlm.nih.gov/pubmed/33584654
http://dx.doi.org/10.3389/fimmu.2020.589863