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Streptococcus pyogenes M1T1 Variants Induce an Inflammatory Neutrophil Phenotype Including Activation of Inflammatory Caspases

Invasive infections due to group A Streptococcus (GAS) advance rapidly causing tissue degradation and unregulated inflammation. Neutrophils are the primary immune cells that respond to GAS. The neutrophil response to GAS was characterised in response to two M1T1 isolates; 5448 and animal passaged va...

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Detalles Bibliográficos
Autores principales: Williams, Jonathan G., Ly, Diane, Geraghty, Nicholas J., McArthur, Jason D., Vyas, Heema K. N., Gorman, Jody, Tsatsaronis, James A., Sluyter, Ronald, Sanderson-Smith, Martina L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876443/
https://www.ncbi.nlm.nih.gov/pubmed/33585270
http://dx.doi.org/10.3389/fcimb.2020.596023