A Non-coding HES1 Variant Predisposes Children to Congenital Heart Disease in Chinese Population

Background: As a key component in the NOTCH signaling pathway, HES1 plays an important role in vertebrate heart development. Variants in the HES1 coding sequence are known to be associated with congenital heart disease (CHD). However, little is known about HES1 non-coding sequence variants and their...

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Detalles Bibliográficos
Autores principales: Song, Yangliu, Chen, Weicheng, Huang, Zitong, Tian, Guixiang, Li, Mengru, Zhao, Zhengshan, Feng, Zhiyu, Wu, Feizhen, Qian, Maoxiang, Ma, Xiaojing, Sheng, Wei, Huang, Guoying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876461/
https://www.ncbi.nlm.nih.gov/pubmed/33585489
http://dx.doi.org/10.3389/fcell.2021.631942

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876461/
https://www.ncbi.nlm.nih.gov/pubmed/33585489
http://dx.doi.org/10.3389/fcell.2021.631942

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