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Trace Elements Status and Metallothioneins DNA Methylation Influence Human Hepatocellular Carcinoma Survival Rate

BACKGROUND: Mechanisms underlying hepatocellular carcinoma (HCC) development are largely unknown. The role of trace elements and proteins regulating metal ions homeostasis, i.e. metallothioneins (MTs), recently gained an increased interest. Object of the study was to investigate the role of promoter...

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Detalles Bibliográficos
Autores principales: Udali, Silvia, De Santis, Domenica, Mazzi, Filippo, Moruzzi, Sara, Ruzzenente, Andrea, Castagna, Annalisa, Pattini, Patrizia, Beschin, Greta, Franceschi, Antonia, Guglielmi, Alfredo, Martinelli, Nicola, Pizzolo, Francesca, Ambrosani, Francesca, Olivieri, Oliviero, Choi, Sang-Woon, Friso, Simonetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876470/
https://www.ncbi.nlm.nih.gov/pubmed/33585212
http://dx.doi.org/10.3389/fonc.2020.596040