Inactivation of the three GGA genes in HeLa cells partially compromises lysosomal enzyme sorting

The Golgi‐localized, gamma‐ear containing, ADP‐ribosylation factor‐binding proteins (GGAs 1, 2, and 3) are multidomain proteins that bind mannose 6‐phosphate receptors (MPRs) at the Golgi and play a role, along with adaptor protein complex 1 (AP‐1), in the sorting of newly synthesized lysosomal hydr...

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Detalles Bibliográficos
Autores principales: Doray, Balraj, Liu, Lin, Lee, Wang‐Sik, Jennings, Benjamin C., Kornfeld, Stuart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876502/
https://www.ncbi.nlm.nih.gov/pubmed/33206455
http://dx.doi.org/10.1002/2211-5463.13040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876502/
https://www.ncbi.nlm.nih.gov/pubmed/33206455
http://dx.doi.org/10.1002/2211-5463.13040

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