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Inactivation of the three GGA genes in HeLa cells partially compromises lysosomal enzyme sorting
The Golgi‐localized, gamma‐ear containing, ADP‐ribosylation factor‐binding proteins (GGAs 1, 2, and 3) are multidomain proteins that bind mannose 6‐phosphate receptors (MPRs) at the Golgi and play a role, along with adaptor protein complex 1 (AP‐1), in the sorting of newly synthesized lysosomal hydr...
Autores principales: | Doray, Balraj, Liu, Lin, Lee, Wang‐Sik, Jennings, Benjamin C., Kornfeld, Stuart |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876502/ https://www.ncbi.nlm.nih.gov/pubmed/33206455 http://dx.doi.org/10.1002/2211-5463.13040 |
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