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Alpha‐synuclein dynamics in induced pluripotent stem cell‐derived dopaminergic neurons from a Parkinson’s disease patient (PARK4) with SNCA triplication

Parkinson's disease (PD) is a neurodegenerative disorder caused by the selective loss of dopaminergic (DA) neurons in the substantia nigra pars compacta (SNc). Lewy bodies (LBs), another histological hallmark of PD, are observed in patients with familial or sporadic PD. The therapeutic potentia...

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Detalles Bibliográficos
Autores principales: Fukusumi, Hayato, Togo, Kazuyuki, Sumida, Miho, Nakamori, Masayuki, Obika, Satoshi, Baba, Kousuke, Shofuda, Tomoko, Ito, Daisuke, Okano, Hideyuki, Mochizuki, Hideki, Kanemura, Yonehiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876504/
https://www.ncbi.nlm.nih.gov/pubmed/33301617
http://dx.doi.org/10.1002/2211-5463.13060