Simultaneously targeting cancer-associated fibroblasts and angiogenic vessel as a treatment for TNBC

Fibrotic tumor stroma plays an important role in facilitating triple-negative breast cancer (TNBC) progression and chemotherapeutic resistance. We previously reported a rationally designed protein (ProAgio) that targets integrin α(v)β(3) at a novel site. ProAgio induces apoptosis via the integrin. C...

Descripción completa

Detalles Bibliográficos
Autores principales: Sharma, Malvika, Turaga, Ravi Chakra, Yuan, Yi, Satyanarayana, Ganesh, Mishra, Falguni, Bian, Zhen, Liu, Wei, Sun, Li, Yang, Jenny, Liu, Zhi-Ren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876552/
https://www.ncbi.nlm.nih.gov/pubmed/33561195
http://dx.doi.org/10.1084/jem.20200712

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876552/
https://www.ncbi.nlm.nih.gov/pubmed/33561195
http://dx.doi.org/10.1084/jem.20200712

Ejemplares similares