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Hypoxia-inducible factor (HIF1alpha) inhibition modulates cumulus cell function and affects bovine oocyte maturation in vitro

Various metabolic and hormonal factors expressed in cumulus cells are positively correlated with the in vitro maturation (IVM) of oocytes. However, the role of hypoxia sensing both during maturation of cumulus–oocyte complexes (COCs) as well as during the resumption of meiosis remains uncertain. HIF...

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Detalles Bibliográficos
Autores principales: Turhan, Aslihan, Pereira, Miguel Tavares, Schuler, Gerhard, Bleul, Ulrich, Kowalewski, Mariusz P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7876663/
https://www.ncbi.nlm.nih.gov/pubmed/33095229
http://dx.doi.org/10.1093/biolre/ioaa196