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Exosomal miR-663b exposed to TGF-β1 promotes cervical cancer metastasis and epithelial-mesenchymal transition by targeting MGAT3

Transforming growth factor (TGF)-β1 is a key cytokine affecting the pathogenesis and progression of cervical cancer. Tumor-derived exosomes contain microRNAs (miRNAs/miRs) that interact with cancer and stromal cells, thereby contributing to tissue remodeling in the tumor microenvironment (TME). The...

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Detalles Bibliográficos
Autores principales: You, Xuewu, Wang, Ying, Meng, Jinyu, Han, Sai, Liu, Lu, Sun, Yu, Zhang, Junhua, Sun, Shuqin, Li, Xinyue, Sun, Wenxiong, Dong, Yajie, Zhang, Youzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877003/
https://www.ncbi.nlm.nih.gov/pubmed/33649791
http://dx.doi.org/10.3892/or.2021.7963